Article:

Human autologous tooth-derived grafts (ATDGs) were recently introduced as a source of bone substitute biomaterial. Using dentin autografts in humans was first reported in 2003. In that first report, demineralized dentin matrix granules were used as a bone substitute biomaterial for sinus augmentation. Since then, a variety of TDGs have been introduced clinically, including block or particulate forms of tooth structures with various levels of mineralization, as shown in Fig 1. In the present article, “TDG” is used as an all-encompassing term to better capture the variability of tooth-derived grafts that can contain the total root structure, dentin only, dentin and cementum, or even enamel.