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Patients often neglect or delay dental care for an extended time because of their negative experiences with and fear of dental treatments. This neglect may result in the advance of periodontitis with severe bone loss, a substantial number of missing teeth, and problems with the remaining teeth. Preexisting malocclusion can aggravate this condition. This case report demonstrates an interdisciplinary strategic approach, in combination with the use of biologically grounded, clinically proven, and viable techniques and technologies to restore optimal esthetics and function in such complex cases. The authors emphasize the importance of carefully planning the timing and sequence of performing periodontal, orthodontic, and implant therapies. The advanced techniques and technologies successfully implemented in this case report include the growth factor and titanium mesh (Ti mesh)-assisted bone augmentation; ovate pontic-mediated, noninvasive soft tissue contouring; and photofunctionalization of dental implants.