Is There One or More Reasons to Optimize the PRF & PRP Protocols? Future Trends in Dentistry, Orthopedics and Facial Aesthetics
The “Advanced” PRF (A-PRF) and “Injectable” PRF (I-PRF) protocols were designed with this new concept. Indications are numerous in all medical fields where we need regeneration: bone, cartilage, skin etc... However, the use of growth factors is not a guarantee of long term stability, as they are active only at the beginning of the process. Numerous rules of tissue engineering have to be applied to maintain the regenerated bone through an adequate blood supply: this lecture is an enlightenment on the biological and mechanical conditions for long term stability of the bone: “grafted bone” or “bone around implants”.

Restoration of Optimal Esthetics in Complex Clinical Situations
Patients often neglect or delay dental care for an extended time because of their negative experiences with and fear of dental treatments. This neglect may result in the advance of periodontitis with severe bone loss, a substantial number of missing teeth, and problems with the remaining teeth. Preexisting malocclusion can aggravate this condition. This case report demonstrates an interdisciplinary strategic approach, in combination with the use of biologically grounded, clinically proven, and viable techniques and technologies to restore optimal esthetics and function in such complex cases. The authors emphasize the importance of carefully planning the timing and sequence of performing periodontal, orthodontic, and implant therapies. The advanced techniques and technologies successfully implemented in this case report include the growth factor and titanium mesh (Ti mesh)-assisted bone augmentation; ovate pontic-mediated, noninvasive soft tissue contouring; and photofunctionalization

Fresh Frozen Allograft Bone plus Bone Marrow Aspiration as a NEW Alternative to Autogenous Bone Augmentation - Part 2 of 2
This lecture presentation will describe the behaviour and utilization of of fresh frozen allograft vs. autogenous bone in major bone augmentation cases. The advantages and disadvantages as well as the potential of adding bone marrow aspirate to fresh frozen bone will be further highlighted. In depth review of how to manage and use this new technique in clinical practice will be clearly explained.

Autologous Bone vs. Bioactive Modifiers/BMP-2: A Clinical Update in Bone Regeneration - Part 2 of 2
There are several techniques and materials available for implant site development. The choice may depend on a number of factors including size of the defect, osseous morphology, costs and surgeon or patient preferences. Autogenous bone has long been considered the gold standard of graft materials. The trend today is to reduce patient morbidity but still provide predictable outcomes. This lecture will discuss the use of autogenous bone versus using bioactive modifiers such as platelet concentrates, rhPDGF and rhBMP-2 as replacement for the need to harvest bone.

Current Concepts in Bioactivity and Regeneration
In this lecture, tips on how to deal with the different types of extraction socket, mostly infected, will be presented. The use of plasma rich in growth factors and the Endoret® (PRGF®) fibrin membrane is a key factor to enhance socket regeneration, post-operative recovery and minimize/treat complications.

Biological Bone Augmentation- Only for REAL BONE BUILDERS
This webinar is addressed to all clinicians, who want to learn safe and predictable bone harvesting and augmentation techniques for different clinical situations. Clear guidelines for the use of augmentative procedures like the Split bone technique by Prof. Khoury and Biological Bone Augmentation with pure autogenous bone and advanced soft tissue management in order to achieve predicable results will be provided.

Clinical and Esthetic Outcomes of the Surgical Veneer Grafting Protocol in the Anterior Maxilla
A multicenter cohort clinical investigation evaluated the change in horizontal ridge dimension associated with immediate implant placement and provisionalization in an anterior extraction socket.

Reconstruction of Damaged Fresh Sockets by Connective-Bone Sliver Graft From the Maxillary Tuberosity, to Enable Immediate Dentoalveolar Restoration - A Clinical Case
This paper describes a procedure for immediate loading of an implant following tooth extraction, in a socket presenting severe damage to the vestibular bone plate and gingival recession in the region of the upper central incisors. The procedures of extraction of the tooth, immediate insertion of the implant, connective- bone graft from the maxillary tuberosity and immediate restoration were shown to be a predictable treatment alternative. These procedures led to restoration of the tooth, bone and gingival structures in a single surgical stage and to maintenance of the favorable esthetic and functional result 24 months afterwards.

Retrospective Evaluation of Crestal Bone Changes Around Implants With Reduced Abutment Diameter Placed Non-Submerged and at Subcrestal Positions: The Effect of Bone Grafting at Implant Placement
One method to measure the success of dental implant treatment is to evaluate marginal peri-implant bone-level changes and stability over time. The location of the fixture–abutment interface (FAI) can be of major importance when the goal is to construct esthetic restorations. In these situations the FAI is often placed in a more apical position to create an ideal emergence profile for the prosthetic construction. However, several animal studies have reported that placement of the FAI in a subcrestal position may result in peri-implant marginal bone loss. The aim of the present study is to evaluate the effect of bone grafting of the defect between the bone crest and the coronal aspect of the implant for implants with reduced abutment diameters placed non-submerged and in subcrestal positions.