Plasma Rich Growth Factors in Reconstructive Implant Therapy
Dr. Eduardo Anitua describes the keys to utilizing plasma derived growth factors (PRGF) in bone augmentation and implant therapy.

Bioengineering and Bone Grafting in Deficient Anterior Sites: A Case Presentation
Dr. Pikos shares a case presentation elucidating the need for bioengineering and osseous grafting to overcome severe deficiencies in anterior sites prior to implant placement. The case is that of a 19 year old caucasian female that presented with congenitally missing maxillary lateral incisors. Both sites were deficient in alveolar width. Subsequent treatment included a single ramus buccal shelf block bone graft that was utilized for bony augmentation along with mineralized allograft and PRGF with collagen membrane. This was followed 4 months later by two 3.8 mm diameter BioHorizons tapered internal Laser-Lok implants. Four year follow up is included.

Synergy of Bone and Gingival Augmentation in Tooth Replacement - Part 1 of 4
This lecture will highlight the current available regenerative techniques and protocols to maximize the esthetic results of tooth replacement therapy.

Current Concepts for the Preservation of the Post-Extraction Alveolar Ridge
Different techniques have been presented in literature in order to preserve the post-extraction site; including the use of barrier membranes, tri-dimensional matrix and bone fillers. An “open-healing” approach is nowadays commonly used, combining a proper management of soft tissues with biological integration of biomaterials. Once hard tissue has been successfully augmented, an adequate soft tissue thickness becomes mandatory in order to create healthy and stable peri-implant tissues. An innovative volume-stable collagen matrix provides the opportunity to treat soft tissue defects around implants as an alternative to connective tissue graft.

Tissue Engineering and Platelet Derived Growth Factors: Evidence Based Therapy
Platelet derived growth factors are now routinely utilized in reconstructive therapy. This presentation describes very detailed and evidence based guidelines for clinicians interested in enhancing their abilities in tissue engineering, especially as it relates to bone augmentation. Specifically, while successful bone augmentation requires the standard surgical parameters of space maintenance, low pressure on the grafts and tension-free flap closure, optimization of this goal requires management and enhancement of the local biological conditions with growth factors. Towards that end, platelet concentrates through the constant release of growth factors are able to promote and enhance new vascularization, provide plasma protein, normal lipidemia, as well as increased collagen and fibrin activity.

Autogenous Bone Harvesting Today
This lecture focuses on autologous bone block harvesting techniques as described by Prof. Khoury: from the donor site identification and harvesting techniques, to an analysis on how computer-guided 3D technology can help the surgeon performing safe and effective mandible bone harvesting procedures.

Post-Traumatic Treatment of Maxillary Incisors by Immediate Dentoalveolar Restoration with Long-Term Follow-Up
Replacing both missing maxillary interior teeth is particularly challenging, especially in compromised sockets. The case report describes the management of an 18-year-old female patient, who suffered avulsion of both maxillary central incisors at 7 years of age. The multidisciplinary implant technique, called Immediate Dentoalveolar Restoration (IDR), included extraction of the injured teeth and a single procedure for immediate implant placement and restoration of the compromised sockets after root fracture and peri-apical lesion development were detected during orthodontic treatment. Successful esthetic and functional outcomes and reestablishment of the alveolar process after bone reconstruction were observed during the 3-year follow-up period. The predictable esthetic outcomes and soft and hard tissue stability that can be achieved following IDR are demonstrated.

Alloplastic Bone Substitutes Around Dental Implants
The repair of osseous defects has been a goal in dentistry for many decades. Subsequently, within the last several years, there has been an emergence of a new class of materials in dentistry referred to as synthetic bone. Finding the ideal bone substitute material has been the goal of researchers for many years. In attempting to achieve this ideal material, dental practitioners have tried with varying degrees of success: autogenous and demineralized freeze-dried bone, allografts of plastic, carbon…

Quantitative Evaluation of Extraction Socket Healing Following the Use of Autologous Platelet-Rich Fibrin Matrix in Humans
Advantages of PRFM alone include less surgical time, elimination of techniques and potential healing difficulties associated with membranes, and less resorption during healing, as compared to guided bone regeneration procedures.